Functional Analysis of the Human Genome

As our understanding of the structure and organization of the human genome grows, studies which can yield insight into genome function become increasingly important. Functional Analysis of the Human Genome reviews the range of techniques currently available for the study of the relationship between structure and function, and assesses the strategies employed to ensure that each of these keeps pace with and complements the other.
Topics covered human genome mapping; cloning transcribed genes; retroviral insertional mutagenesis; gene trapping; gene transfer and expression; integration of foreign DNA and DNA methylation; use of transgenic animals in human gene analysis; homologous recombination and its applications (including gene therapy); use of antisense oligonucleotides.
Functional Analysis of the Human Genome is a timely and detailed account of this key area of study. Written by active researchers in the filed, the aim has been to produce a book which is both authoritative and succeeds in provoking genuine excitement about this topic. Experienced researchers and newcomers to the subject alike will find this volume to be essential reading.